An evaluation of approaches for rare variant association analyses of binary traits in related samples
Abstract Recognizing that family data provide unique advantage of identifying rare risk variants in genetic association studies, many cohorts with related samples have gone through whole genome sequencing in large initiatives such as the NHLBI Trans-Omics for Precision Medicine (TOPMed) program. Ana...
Guardado en:
Autores principales: | Ming-Huei Chen, Achilleas Pitsillides, Qiong Yang |
---|---|
Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2021
|
Materias: | |
Acceso en línea: | https://doaj.org/article/72b245b1894a491e9d3931f638fb49ac |
Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
Ejemplares similares
-
Multi-trait analysis of rare-variant association summary statistics using MTAR
por: Lan Luo, et al.
Publicado: (2020) -
A linkage disequilibrium-based approach to selecting disease-associated rare variants.
por: Rajesh Talluri, et al.
Publicado: (2013) -
Prevalence and associations of COVID-19 testing in an online sample of transgender and non-binary individuals
por: S Wilson Beckham, et al.
Publicado: (2021) -
Novel autism subtype-dependent genetic variants are revealed by quantitative trait and subphenotype association analyses of published GWAS data.
por: Valerie W Hu, et al.
Publicado: (2011) -
Rare variants in the endocytic pathway are associated with Alzheimer's disease, its related phenotypes, and functional consequences.
por: Lingyu Zhan, et al.
Publicado: (2021)