Acute cigarette smoke or extract exposure rapidly activates TRPA1-mediated calcium influx in primary human airway smooth muscle cells

Abstract Tobacco smoking is the largest risk factor for developing chronic obstructive pulmonary disease (COPD), and is associated with hyperresponsiveness of airway smooth muscle (ASM). Chronic exposure to cigarette smoke (CS) leads to airway inflammation and remodelling. However, the direct effect...

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Autores principales: JinHeng Lin, Michael Taggart, Lee Borthwick, Andrew Fisher, Malcolm Brodlie, M. Flori Sassano, Robert Tarran, Michael A. Gray
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/72b7419af6304da68bba73654931260e
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