The impact of HIF1α on the Per2 circadian rhythm in renal cancer cell lines.

In mammals, the circadian rhythm central generator consists of interactions among clock genes, including Per1/2/3, Cry1/2, Bmal1, and Clock. Circadian rhythm disruption may lead to increased risk of cancer in humans, and deregulation of clock genes has been implicated in many types of cancers. Among...

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Autores principales: Takashi Okabe, Megumi Kumagai, Yoshihiro Nakajima, Suguru Shirotake, Kiichiro Kodaira, Masafumi Oyama, Munehisa Ueno, Masaaki Ikeda
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2014
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Acceso en línea:https://doaj.org/article/72d8721dc05a44ef8bbd201ada9b2035
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