C-edge loops of arrestin function as a membrane anchor

The activity of G-protein-coupled receptors is regulated by their interaction with arrestins. Here the authors show that loops located on C-edge of arrestin-1 serve as a membrane anchor during the multi-step binding process that leads to a stable receptor–arrestin complex.

Guardado en:
Detalles Bibliográficos
Autores principales: Ciara C M. Lally, Brian Bauer, Jana Selent, Martha E Sommer
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
Materias:
Q
Acceso en línea:https://doaj.org/article/72e83b7d836d45689db64162e5a82405
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!