C-edge loops of arrestin function as a membrane anchor

The activity of G-protein-coupled receptors is regulated by their interaction with arrestins. Here the authors show that loops located on C-edge of arrestin-1 serve as a membrane anchor during the multi-step binding process that leads to a stable receptor–arrestin complex.

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Auteurs principaux: Ciara C M. Lally, Brian Bauer, Jana Selent, Martha E Sommer
Format: article
Langue:EN
Publié: Nature Portfolio 2017
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Accès en ligne:https://doaj.org/article/72e83b7d836d45689db64162e5a82405
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