Conditional Deletion of Pdcd1 Identifies the Cell-Intrinsic Action of PD-1 on Functional CD8 T Cell Subsets for Antitumor Efficacy

Programmed cell death-1 (PD-1) blockade has a profound effect on the ability of the immune system to eliminate tumors, but many questions remain about the cell types involved and the underlying mechanisms of immune activation. To shed some light on this, the cellular and molecular events following i...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autores principales: Sukanya Raghavan, Nataliya Tovbis-Shifrin, Christina Kochel, Anandi Sawant, Marielle Mello, Manjiri Sathe, Wendy Blumenschein, Eric S. Muise, Alissa Chackerian, Elaine M. Pinheiro, Thomas W. Rosahl, Hervé Luche, Rene de Waal Malefyt
Formato: article
Lenguaje:EN
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://doaj.org/article/72fd7ab5d05749e780b38e08a7d4a277
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!