Ubiquitous [Na+]i/[K+]i-sensitive transcriptome in mammalian cells: evidence for Ca(2+)i-independent excitation-transcription coupling.

Stimulus-dependent elevation of intracellular Ca(2+) ([Ca(2+)](i)) affects the expression of numerous genes--a phenomenon known as excitation-transcription coupling. Recently, we found that increases in [Na(+)](i) trigger c-Fos expression via a novel Ca(2+) (i)-independent pathway. In the present st...

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Autores principales: Svetlana V Koltsova, Yulia Trushina, Mounsif Haloui, Olga A Akimova, Johanne Tremblay, Pavel Hamet, Sergei N Orlov
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2012
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Acceso en línea:https://doaj.org/article/72fdc3bfb05a4583b13bb504ccdfb00d
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