Structural basis of tubulin detyrosination by VASH2/SVBP heterodimer

The VASH2/SVBP heterodimer catalyzes the detyrosination of the α-tubulin C-terminus. Here the authors provide insights into the tubulin detyrosination mechanism by determining the crystal structures of VASH2/SVBP and VASH2/SVBP in complex with a tubulin tail peptide.

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Détails bibliographiques
Auteurs principaux: Chen Zhou, Ling Yan, Wen-hui Zhang, Zhu Liu
Format: article
Langue:EN
Publié: Nature Portfolio 2019
Sujets:
Q
Accès en ligne:https://doaj.org/article/73149a2dc2634b788e4b85463c6af74a
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