Structural basis of tubulin detyrosination by VASH2/SVBP heterodimer

The VASH2/SVBP heterodimer catalyzes the detyrosination of the α-tubulin C-terminus. Here the authors provide insights into the tubulin detyrosination mechanism by determining the crystal structures of VASH2/SVBP and VASH2/SVBP in complex with a tubulin tail peptide.

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Detalles Bibliográficos
Autores principales: Chen Zhou, Ling Yan, Wen-hui Zhang, Zhu Liu
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2019
Materias:
Q
Acceso en línea:https://doaj.org/article/73149a2dc2634b788e4b85463c6af74a
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