Structural basis of tubulin detyrosination by VASH2/SVBP heterodimer

The VASH2/SVBP heterodimer catalyzes the detyrosination of the α-tubulin C-terminus. Here the authors provide insights into the tubulin detyrosination mechanism by determining the crystal structures of VASH2/SVBP and VASH2/SVBP in complex with a tubulin tail peptide.

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Detalles Bibliográficos
Autores principales:	Chen Zhou, Ling Yan, Wen-hui Zhang, Zhu Liu
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2019
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/73149a2dc2634b788e4b85463c6af74a
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spelling	oai:doaj.org-article:73149a2dc2634b788e4b85463c6af74a2021-12-02T16:50:58ZStructural basis of tubulin detyrosination by VASH2/SVBP heterodimer10.1038/s41467-019-11277-82041-1723https://doaj.org/article/73149a2dc2634b788e4b85463c6af74a2019-07-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-11277-8https://doaj.org/toc/2041-1723The VASH2/SVBP heterodimer catalyzes the detyrosination of the α-tubulin C-terminus. Here the authors provide insights into the tubulin detyrosination mechanism by determining the crystal structures of VASH2/SVBP and VASH2/SVBP in complex with a tubulin tail peptide.Chen ZhouLing YanWen-hui ZhangZhu LiuNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-8 (2019)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Chen Zhou Ling Yan Wen-hui Zhang Zhu Liu Structural basis of tubulin detyrosination by VASH2/SVBP heterodimer
description	The VASH2/SVBP heterodimer catalyzes the detyrosination of the α-tubulin C-terminus. Here the authors provide insights into the tubulin detyrosination mechanism by determining the crystal structures of VASH2/SVBP and VASH2/SVBP in complex with a tubulin tail peptide.
format	article
author	Chen Zhou Ling Yan Wen-hui Zhang Zhu Liu
author_facet	Chen Zhou Ling Yan Wen-hui Zhang Zhu Liu
author_sort	Chen Zhou
title	Structural basis of tubulin detyrosination by VASH2/SVBP heterodimer
title_short	Structural basis of tubulin detyrosination by VASH2/SVBP heterodimer
title_full	Structural basis of tubulin detyrosination by VASH2/SVBP heterodimer
title_fullStr	Structural basis of tubulin detyrosination by VASH2/SVBP heterodimer
title_full_unstemmed	Structural basis of tubulin detyrosination by VASH2/SVBP heterodimer
title_sort	structural basis of tubulin detyrosination by vash2/svbp heterodimer
publisher	Nature Portfolio
publishDate	2019
url	https://doaj.org/article/73149a2dc2634b788e4b85463c6af74a
work_keys_str_mv	AT chenzhou structuralbasisoftubulindetyrosinationbyvash2svbpheterodimer AT lingyan structuralbasisoftubulindetyrosinationbyvash2svbpheterodimer AT wenhuizhang structuralbasisoftubulindetyrosinationbyvash2svbpheterodimer AT zhuliu structuralbasisoftubulindetyrosinationbyvash2svbpheterodimer
_version_	1718382984381333504

Structural basis of tubulin detyrosination by VASH2/SVBP heterodimer

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