Structural basis of tubulin detyrosination by VASH2/SVBP heterodimer
The VASH2/SVBP heterodimer catalyzes the detyrosination of the α-tubulin C-terminus. Here the authors provide insights into the tubulin detyrosination mechanism by determining the crystal structures of VASH2/SVBP and VASH2/SVBP in complex with a tubulin tail peptide.
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Autores principales: | Chen Zhou, Ling Yan, Wen-hui Zhang, Zhu Liu |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2019
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Materias: | |
Acceso en línea: | https://doaj.org/article/73149a2dc2634b788e4b85463c6af74a |
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