Increased oxidative metabolism and neurotransmitter cycling in the brain of mice lacking the thyroid hormone transporter SLC16A2 (MCT8).

Mutations of the monocarboxylate transporter 8 (MCT8) cause a severe X-linked intellectual deficit and neurological impairment. MCT8 is a specific thyroid hormone (T4 and T3) transporter and the patients also present unusual abnormalities in the serum profile of thyroid hormone concentrations due to...

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Autores principales: Tiago B Rodrigues, Ainhoa Ceballos, Carmen Grijota-Martínez, Barbara Nuñez, Samuel Refetoff, Sebastian Cerdán, Beatriz Morte, Juan Bernal
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2013
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Acceso en línea:https://doaj.org/article/731bcf4cf7ca4c42ab7b10cb91daafb6
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