FAM-MDR: a flexible family-based multifactor dimensionality reduction technique to detect epistasis using related individuals.
We propose a novel multifactor dimensionality reduction method for epistasis detection in small or extended pedigrees, FAM-MDR. It combines features of the Genome-wide Rapid Association using Mixed Model And Regression approach (GRAMMAR) with Model-Based MDR (MB-MDR). We focus on continuous traits,...
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| Main Authors: | , , , , , , , , , , , |
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| Format: | article |
| Language: | EN |
| Published: |
Public Library of Science (PLoS)
2010
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| Subjects: | |
| Online Access: | https://doaj.org/article/73364a32f96349eebd6e6cf8ab957a95 |
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