High grade serous ovarian carcinomas originate in the fallopian tube

It has previously been proposed that high-grade serous ovarian carcinoma (HGSOC) may originate from the fallopian tube. Here, the authors analyze genetic aberrances in fallopian tube lesions, ovarian cancers, and metastases from HGSOC patients and establish the evolutionary origins of HGSOC in the f...

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Autores principales: S. Intidhar Labidi-Galy, Eniko Papp, Dorothy Hallberg, Noushin Niknafs, Vilmos Adleff, Michael Noe, Rohit Bhattacharya, Marian Novak, Siân Jones, Jillian Phallen, Carolyn A. Hruban, Michelle S. Hirsch, Douglas I. Lin, Lauren Schwartz, Cecile L. Maire, Jean-Christophe Tille, Michaela Bowden, Ayse Ayhan, Laura D. Wood, Robert B. Scharpf, Robert Kurman, Tian-Li Wang, Ie-Ming Shih, Rachel Karchin, Ronny Drapkin, Victor E. Velculescu
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
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Acceso en línea:https://doaj.org/article/733833a56c6b45119ce856baf3827bd9
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spelling oai:doaj.org-article:733833a56c6b45119ce856baf3827bd92021-12-02T14:40:23ZHigh grade serous ovarian carcinomas originate in the fallopian tube10.1038/s41467-017-00962-12041-1723https://doaj.org/article/733833a56c6b45119ce856baf3827bd92017-10-01T00:00:00Zhttps://doi.org/10.1038/s41467-017-00962-1https://doaj.org/toc/2041-1723It has previously been proposed that high-grade serous ovarian carcinoma (HGSOC) may originate from the fallopian tube. Here, the authors analyze genetic aberrances in fallopian tube lesions, ovarian cancers, and metastases from HGSOC patients and establish the evolutionary origins of HGSOC in the fallopian tube.S. Intidhar Labidi-GalyEniko PappDorothy HallbergNoushin NiknafsVilmos AdleffMichael NoeRohit BhattacharyaMarian NovakSiân JonesJillian PhallenCarolyn A. HrubanMichelle S. HirschDouglas I. LinLauren SchwartzCecile L. MaireJean-Christophe TilleMichaela BowdenAyse AyhanLaura D. WoodRobert B. ScharpfRobert KurmanTian-Li WangIe-Ming ShihRachel KarchinRonny DrapkinVictor E. VelculescuNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-11 (2017)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
S. Intidhar Labidi-Galy
Eniko Papp
Dorothy Hallberg
Noushin Niknafs
Vilmos Adleff
Michael Noe
Rohit Bhattacharya
Marian Novak
Siân Jones
Jillian Phallen
Carolyn A. Hruban
Michelle S. Hirsch
Douglas I. Lin
Lauren Schwartz
Cecile L. Maire
Jean-Christophe Tille
Michaela Bowden
Ayse Ayhan
Laura D. Wood
Robert B. Scharpf
Robert Kurman
Tian-Li Wang
Ie-Ming Shih
Rachel Karchin
Ronny Drapkin
Victor E. Velculescu
High grade serous ovarian carcinomas originate in the fallopian tube
description It has previously been proposed that high-grade serous ovarian carcinoma (HGSOC) may originate from the fallopian tube. Here, the authors analyze genetic aberrances in fallopian tube lesions, ovarian cancers, and metastases from HGSOC patients and establish the evolutionary origins of HGSOC in the fallopian tube.
format article
author S. Intidhar Labidi-Galy
Eniko Papp
Dorothy Hallberg
Noushin Niknafs
Vilmos Adleff
Michael Noe
Rohit Bhattacharya
Marian Novak
Siân Jones
Jillian Phallen
Carolyn A. Hruban
Michelle S. Hirsch
Douglas I. Lin
Lauren Schwartz
Cecile L. Maire
Jean-Christophe Tille
Michaela Bowden
Ayse Ayhan
Laura D. Wood
Robert B. Scharpf
Robert Kurman
Tian-Li Wang
Ie-Ming Shih
Rachel Karchin
Ronny Drapkin
Victor E. Velculescu
author_facet S. Intidhar Labidi-Galy
Eniko Papp
Dorothy Hallberg
Noushin Niknafs
Vilmos Adleff
Michael Noe
Rohit Bhattacharya
Marian Novak
Siân Jones
Jillian Phallen
Carolyn A. Hruban
Michelle S. Hirsch
Douglas I. Lin
Lauren Schwartz
Cecile L. Maire
Jean-Christophe Tille
Michaela Bowden
Ayse Ayhan
Laura D. Wood
Robert B. Scharpf
Robert Kurman
Tian-Li Wang
Ie-Ming Shih
Rachel Karchin
Ronny Drapkin
Victor E. Velculescu
author_sort S. Intidhar Labidi-Galy
title High grade serous ovarian carcinomas originate in the fallopian tube
title_short High grade serous ovarian carcinomas originate in the fallopian tube
title_full High grade serous ovarian carcinomas originate in the fallopian tube
title_fullStr High grade serous ovarian carcinomas originate in the fallopian tube
title_full_unstemmed High grade serous ovarian carcinomas originate in the fallopian tube
title_sort high grade serous ovarian carcinomas originate in the fallopian tube
publisher Nature Portfolio
publishDate 2017
url https://doaj.org/article/733833a56c6b45119ce856baf3827bd9
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