HB-EGF-induced IL-8 secretion from airway epithelium leads to lung fibroblast proliferation and migration

Abstract Background We have reported that heparin-binding epidermal growth factor (HB-EGF) is increased in patients with chronic obstructive pulmonary disease (COPD) and associated with collagen deposition, but the mechanisms remain unclear. In the present study, we aimed to investigated the inflamm...

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Auteurs principaux: Yanyu Li, Guomei Su, Yu Zhong, Zhilin Xiong, Tong Huang, Jingyun Quan, Jiewen Huang, Xiaoxia Wen, Chaole Luo, Weilin Zheng, Jinfeng Chen, Junfen Cheng, Weimin Yao, Tianwen Lai
Format: article
Langue:EN
Publié: BMC 2021
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Accès en ligne:https://doaj.org/article/733cb9ea5b4e46acbf785e42bce2d5c7
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