Characterization of Novel P-Selectin Targeted Complement Inhibitors in Murine Models of Hindlimb Injury and Transplantation

The complement system has long been recognized as a potential druggable target for a variety of inflammatory conditions. Very few complement inhibitors have been approved for clinical use, but a great number are in clinical development, nearly all of which systemically inhibit complement. There are...

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Auteurs principaux: Chaowen Zheng, Jerec Ricci, Qinqin Zhang, Ali Alawieh, Xiaofeng Yang, Satish Nadig, Songqing He, Pablo Engel, Junfei Jin, Carl Atkinson, Stephen Tomlinson
Format: article
Langue:EN
Publié: Frontiers Media S.A. 2021
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Accès en ligne:https://doaj.org/article/7361eaa42a2e421581d4b21788419f78
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