Transgenic Chickens Expressing the 3D8 Single Chain Variable Fragment Protein Suppress Avian Influenza Transmission

Transgenic Chickens Expressing the 3D8 Single Chain Variable Fragment Protein Suppress Avian Influenza Transmission

Abstract The 3D8 single chain variable fragment (scFv) is a mini-antibody that causes unusual sequence-independent nuclease activity against all types of nucleic acids. We used recombinant lentiviruses to generate transgenic chickens expressing the 3D8 scFv gene under the control of the chicken β-ac...

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Main Authors: Sung June Byun, Seong-su Yuk, Ye-Jin Jang, Hoonsung Choi, Mi-Hyang Jeon, TO Erdene-Ochir, Jung-Hoon Kwon, Jin-Yong Noh, Jeom Sun Kim, Jae Gyu YOO, Chang-Seon Song
Format: article
Language:EN
Published: Nature Portfolio 2017
Subjects:
Medicine
R
Science
Q
Online Access:https://doaj.org/article/73cef92afc1a48b7a251dd78228c0bb3
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https://doaj.org/article/73cef92afc1a48b7a251dd78228c0bb3

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