Mexiletine-like cellular electrophysiological effects of GS967 in canine ventricular myocardium

Mexiletine-like cellular electrophysiological effects of GS967 in canine ventricular myocardium

Abstract Enhancement of the late Na+ current (INaL) increases arrhythmia propensity in the heart, while suppression of the current is antiarrhythmic. GS967 is an agent considered as a selective blocker of INaL. In the present study, effects of GS967 on INaL and action potential (AP) morphology were...

Description complète

Enregistré dans:
Détails bibliographiques
Auteurs principaux: Tamás Hézső, Muhammad Naveed, Csaba Dienes, Dénes Kiss, János Prorok, Tamás Árpádffy-Lovas, Richárd Varga, Erika Fujii, Tanju Mercan, Leila Topal, Kornél Kistamás, Norbert Szentandrássy, János Almássy, Norbert Jost, János Magyar, Tamás Bányász, István Baczkó, András Varró, Péter P. Nánási, László Virág, Balázs Horváth
Format: article
Langue:EN
Publié: Nature Portfolio 2021
Sujets:
Medicine
R
Science
Q
Accès en ligne:https://doaj.org/article/73d50e33846d4bc7818bb17c0e8b0687
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!

Internet

https://doaj.org/article/73d50e33846d4bc7818bb17c0e8b0687

Documents similaires