Single-molecule live-cell imaging visualizes parallel pathways of prokaryotic nucleotide excision repair

In Escherichia coli, the UvrAB damage sensor recognizes helix-distorting lesions by itself or via Mfd bound to stalled RNA polymerase. Here authors use single-molecule fluorescence imaging to quantify the kinetic signatures of interactions of UvrA with Mfd and UvrB in live cells.

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Autores principales: Harshad Ghodke, Han Ngoc Ho, Antoine M. van Oijen
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2020
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Acceso en línea:https://doaj.org/article/740952bd81dd4cec999c0b5ba80ed116
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