Longer Poly(U) Stretches in the 3′UTR Are Essential for Replication of the Hepatitis C Virus Genotype 4a Clone in in vitro and in vivo

The 3′ untranslated region (UTR) of the hepatitis C virus (HCV) genome plays a significant role in replication including the poly(U) tract (You and Rice, 2008). Here we established an HCV clone that is infectious in vitro and in vivo, from an Egyptian patient with chronic HCV infection and hepatocel...

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Autores principales: Asako Takagi, Yutaka Amako, Daisuke Yamane, Bouchra Kitab, Yuko Tokunaga, Ahmed El-Gohary, Michinori Kohara, Kyoko Tsukiyama-Kohara
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Lenguaje:EN
Publicado: Frontiers Media S.A. 2021
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Acceso en línea:https://doaj.org/article/741d49c789764deaa0ea151313a3ca33
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