A milk formula containing maltodextrin, vs. lactose, as main carbohydrate source, improves cognitive performance of piglets in a spatial task

Abstract In recent years, lactose-free and low-lactose infant formulas have been increasingly used. The impact of using different carbohydrates than lactose on later cognition of formula-fed infants remains, however, unknown. We examined the effects of providing formulas containing either digestible...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Caroline Clouard, Cindy Le Bourgot, Frédérique Respondek, J. Elizabeth Bolhuis, Walter J. J. Gerrits
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2018
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/744b2dbaf1984b5ca5749caf7d258845
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:744b2dbaf1984b5ca5749caf7d258845
record_format	dspace
spelling	oai:doaj.org-article:744b2dbaf1984b5ca5749caf7d2588452021-12-02T15:07:58ZA milk formula containing maltodextrin, vs. lactose, as main carbohydrate source, improves cognitive performance of piglets in a spatial task10.1038/s41598-018-27796-12045-2322https://doaj.org/article/744b2dbaf1984b5ca5749caf7d2588452018-06-01T00:00:00Zhttps://doi.org/10.1038/s41598-018-27796-1https://doaj.org/toc/2045-2322Abstract In recent years, lactose-free and low-lactose infant formulas have been increasingly used. The impact of using different carbohydrates than lactose on later cognition of formula-fed infants remains, however, unknown. We examined the effects of providing formulas containing either digestible maltodextrin or lactose as main carbohydrate source (28% of total nutrient composition) on cognitive performance of piglets. Piglets received the formulas from 1 to 9 weeks of age and, starting at 12 weeks, were individually tested in a spatial holeboard task (n = 8 pens/formula), in which they had to learn and memorize a configuration of baited buckets. After 28 acquisition trials, piglets were subjected to 16 reversal trials in which the location of the baited buckets was changed. Piglets fed the maltodextrin-based formula had higher reference memory (RM) scores than piglets fed the lactose-based formula towards the end of acquisition. During the switch of configuration, piglets offered the maltodextrin-based formula tended to have higher RM scores and make fewer RM errors than piglets offered the lactose-based formula. Working (short-term) memory was not affected by the formulas. Compared to lactose, the use of maltodextrin in milk formulas improved long-term spatial memory of piglets, even weeks after the end of the intervention.Caroline ClouardCindy Le BourgotFrédérique RespondekJ. Elizabeth BolhuisWalter J. J. GerritsNature PortfolioarticleMedicineRScienceQENScientific Reports, Vol 8, Iss 1, Pp 1-12 (2018)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Caroline Clouard Cindy Le Bourgot Frédérique Respondek J. Elizabeth Bolhuis Walter J. J. Gerrits A milk formula containing maltodextrin, vs. lactose, as main carbohydrate source, improves cognitive performance of piglets in a spatial task
description	Abstract In recent years, lactose-free and low-lactose infant formulas have been increasingly used. The impact of using different carbohydrates than lactose on later cognition of formula-fed infants remains, however, unknown. We examined the effects of providing formulas containing either digestible maltodextrin or lactose as main carbohydrate source (28% of total nutrient composition) on cognitive performance of piglets. Piglets received the formulas from 1 to 9 weeks of age and, starting at 12 weeks, were individually tested in a spatial holeboard task (n = 8 pens/formula), in which they had to learn and memorize a configuration of baited buckets. After 28 acquisition trials, piglets were subjected to 16 reversal trials in which the location of the baited buckets was changed. Piglets fed the maltodextrin-based formula had higher reference memory (RM) scores than piglets fed the lactose-based formula towards the end of acquisition. During the switch of configuration, piglets offered the maltodextrin-based formula tended to have higher RM scores and make fewer RM errors than piglets offered the lactose-based formula. Working (short-term) memory was not affected by the formulas. Compared to lactose, the use of maltodextrin in milk formulas improved long-term spatial memory of piglets, even weeks after the end of the intervention.
format	article
author	Caroline Clouard Cindy Le Bourgot Frédérique Respondek J. Elizabeth Bolhuis Walter J. J. Gerrits
author_facet	Caroline Clouard Cindy Le Bourgot Frédérique Respondek J. Elizabeth Bolhuis Walter J. J. Gerrits
author_sort	Caroline Clouard
title	A milk formula containing maltodextrin, vs. lactose, as main carbohydrate source, improves cognitive performance of piglets in a spatial task
title_short	A milk formula containing maltodextrin, vs. lactose, as main carbohydrate source, improves cognitive performance of piglets in a spatial task
title_full	A milk formula containing maltodextrin, vs. lactose, as main carbohydrate source, improves cognitive performance of piglets in a spatial task
title_fullStr	A milk formula containing maltodextrin, vs. lactose, as main carbohydrate source, improves cognitive performance of piglets in a spatial task
title_full_unstemmed	A milk formula containing maltodextrin, vs. lactose, as main carbohydrate source, improves cognitive performance of piglets in a spatial task
title_sort	milk formula containing maltodextrin, vs. lactose, as main carbohydrate source, improves cognitive performance of piglets in a spatial task
publisher	Nature Portfolio
publishDate	2018
url	https://doaj.org/article/744b2dbaf1984b5ca5749caf7d258845
work_keys_str_mv	AT carolineclouard amilkformulacontainingmaltodextrinvslactoseasmaincarbohydratesourceimprovescognitiveperformanceofpigletsinaspatialtask AT cindylebourgot amilkformulacontainingmaltodextrinvslactoseasmaincarbohydratesourceimprovescognitiveperformanceofpigletsinaspatialtask AT frederiquerespondek amilkformulacontainingmaltodextrinvslactoseasmaincarbohydratesourceimprovescognitiveperformanceofpigletsinaspatialtask AT jelizabethbolhuis amilkformulacontainingmaltodextrinvslactoseasmaincarbohydratesourceimprovescognitiveperformanceofpigletsinaspatialtask AT walterjjgerrits amilkformulacontainingmaltodextrinvslactoseasmaincarbohydratesourceimprovescognitiveperformanceofpigletsinaspatialtask AT carolineclouard milkformulacontainingmaltodextrinvslactoseasmaincarbohydratesourceimprovescognitiveperformanceofpigletsinaspatialtask AT cindylebourgot milkformulacontainingmaltodextrinvslactoseasmaincarbohydratesourceimprovescognitiveperformanceofpigletsinaspatialtask AT frederiquerespondek milkformulacontainingmaltodextrinvslactoseasmaincarbohydratesourceimprovescognitiveperformanceofpigletsinaspatialtask AT jelizabethbolhuis milkformulacontainingmaltodextrinvslactoseasmaincarbohydratesourceimprovescognitiveperformanceofpigletsinaspatialtask AT walterjjgerrits milkformulacontainingmaltodextrinvslactoseasmaincarbohydratesourceimprovescognitiveperformanceofpigletsinaspatialtask
_version_	1718388322794995712

A milk formula containing maltodextrin, vs. lactose, as main carbohydrate source, improves cognitive performance of piglets in a spatial task

Ejemplares similares