Exploring redox vulnerabilities in JAK2V617F-positive cellular models
Background: In Philadelphia chromosome-negative myeloproliferative neoplasm (MPN) models, reactive oxygen species (ROS) are elevated and have been implicated in genomic instability, JAK2/STAT signaling amplification, and disease progression. Although the potential effects of ROS on the MPN phenotype...
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Auteurs principaux: | , , |
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Format: | article |
Langue: | EN |
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Elsevier
2021
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Accès en ligne: | https://doaj.org/article/746525e0d6704806a6bbd83cbf149bca |
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