Exploring redox vulnerabilities in JAK2V617F-positive cellular models

Background: In Philadelphia chromosome-negative myeloproliferative neoplasm (MPN) models, reactive oxygen species (ROS) are elevated and have been implicated in genomic instability, JAK2/STAT signaling amplification, and disease progression. Although the potential effects of ROS on the MPN phenotype...

Description complète

Enregistré dans:
Détails bibliographiques
Auteurs principaux: Keli Lima, Lucia Rossetti Lopes, João Agostinho Machado-Neto
Format: article
Langue:EN
Publié: Elsevier 2021
Sujets:
Accès en ligne:https://doaj.org/article/746525e0d6704806a6bbd83cbf149bca
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!