Common variants in MMP20 at 11q22.2 predispose to 11q deletion and neuroblastoma risk

Common variants in MMP20 at 11q22.2 predispose to 11q deletion and neuroblastoma risk

Chromosomal abnormalities such as 11q deletion are associated with poor prognosis in neuroblastoma. Here, the authors perform a genome-wide association study and identify an association between a variant within a Matrix metalloproteinase (MMP) gene member, MMP20, and 11q-deletion subtype neuroblasto...

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Auteurs principaux: Xiao Chang, Yan Zhao, Cuiping Hou, Joseph Glessner, Lee McDaniel, Maura A. Diamond, Kelly Thomas, Jin Li, Zhi Wei, Yichuan Liu, Yiran Guo, Frank D. Mentch, Haijun Qiu, Cecilia Kim, Perry Evans, Zalman Vaksman, Sharon J. Diskin, Edward F. Attiyeh, Patrick Sleiman, John M. Maris, Hakon Hakonarson
Format: article
Langue:EN
Publié: Nature Portfolio 2017
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Science
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Accès en ligne:https://doaj.org/article/7488eacd07eb497cac82b43d8ef8c81f
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https://doaj.org/article/7488eacd07eb497cac82b43d8ef8c81f

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