Broad-Host-Range Expression Reveals Native and Host Regulatory Elements That Influence Heterologous Antibiotic Production in Gram-Negative Bacteria
ABSTRACT Heterologous expression has become a powerful tool for studying microbial biosynthetic gene clusters (BGCs). Here, we extend the transformation-associated recombination cloning and heterologous expression platform for microbial BGCs to include Gram-negative proteobacterial expression hosts....
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Main Authors: | Jia Jia Zhang, Xiaoyu Tang, Michelle Zhang, Darlene Nguyen, Bradley S. Moore |
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Format: | article |
Language: | EN |
Published: |
American Society for Microbiology
2017
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Online Access: | https://doaj.org/article/748b1cccf587411e8ba73b0dbd938e30 |
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