Avoiding dangerous missense: thermophiles display especially low mutation rates.
Rates of spontaneous mutation have been estimated under optimal growth conditions for a variety of DNA-based microbes, including viruses, bacteria, and eukaryotes. When expressed as genomic mutation rates, most of the values were in the vicinity of 0.003-0.004 with a range of less than two-fold. Bec...
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Format: | article |
Langue: | EN |
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Public Library of Science (PLoS)
2009
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Accès en ligne: | https://doaj.org/article/748cf4662e9842ac9fb7a89cfb238375 |
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