Prostaglandin F2α agonists induced enhancement in collagen1 expression is involved in the pathogenesis of the deepening of upper eyelid sulcus

Abstract Previous our study reported that three-dimension (3D) cultures of human orbital fibroblasts (HOFs) replicated the etiology of deepening of the upper eyelid sulcus (DUES) caused by prostaglandin F2α analogues (PGF2α-ags). To examine this further, the effects of PGF2α-ags on HOFs were charact...

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Bibliographic Details
Main Authors: Kaku Itoh, Yosuke Ida, Hiroshi Ohguro, Fumihito Hikage
Format: article
Language:EN
Published: Nature Portfolio 2021
Subjects:
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Online Access:https://doaj.org/article/74b29f2fbaac40889ecda51ca5b4a797
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