Modification of improved-genome editing via oviductal nucleic acids delivery (i-GONAD)-mediated knock-in in rats

Abstract Background Improved genome-editing via oviductal nucleic acids delivery (i-GONAD) is a new technology that facilitates in situ genome-editing of mammalian zygotes exiting the oviductal lumen. The i-GONAD technology has been developed for use in mice, rats, and hamsters; however, oligonucleo...

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Autores principales: Takuya Aoshima, Yukari Kobayashi, Hisayoshi Takagi, Kenta Iijima, Masahiro Sato, Shuji Takabayashi
Formato: article
Lenguaje:EN
Publicado: BMC 2021
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Acceso en línea:https://doaj.org/article/74c5e216897a4123a7217565ce07b8c6
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