The H3K9 methyltransferase SETDB1 maintains female identity in Drosophila germ cells

Epigenetic regulation is critical for the maintenance of germ cell identity. Here the authors show that H3K9me3-mediated gene silencing is critical for repression of testis-specific transcription in Drosophila female germ cells, indicating H3K9me3 maintains female germ cell sexual identity.

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Auteurs principaux: Anne E. Smolko, Laura Shapiro-Kulnane, Helen K. Salz
Format: article
Langue:EN
Publié: Nature Portfolio 2018
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Accès en ligne:https://doaj.org/article/74ebcd160d7e4074aa11e9e361e200e3
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