Syringeable immunotherapeutic nanogel reshapes tumor microenvironment and prevents tumor metastasis and recurrence

The limited efficacy of current immunotherapy suggests low antigen-specific T cells and immunosuppressive factors in tumor microenvironment (TME). Here, the authors develop a syringeable immunomodulatory multi-domain nanogel that can reprogram the TME and induce enhanced cancer immunotherapy.

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Auteurs principaux: Chanyoung Song, Hathaichanok Phuengkham, Young Seob Kim, Van Vuong Dinh, Inho Lee, Il Woo Shin, Hong Sik Shin, Seung Mo Jin, Soong Ho Um, Hyunseung Lee, Kwan Soo Hong, Seon-Mi Jin, Eunji Lee, Tae Heung Kang, Yeong-Min Park, Yong Taik Lim
Format: article
Langue:EN
Publié: Nature Portfolio 2019
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Accès en ligne:https://doaj.org/article/74f56ede70494663b8680f81b8197124
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