miRNA-29c suppresses lung cancer cell adhesion to extracellular matrix and metastasis by targeting integrin β1 and matrix metalloproteinase2 (MMP2).

miRNA-29c suppresses lung cancer cell adhesion to extracellular matrix and metastasis by targeting integrin β1 and matrix metalloproteinase2 (MMP2).

Our pilot study using miRNA arrays found that miRNA-29c (miR-29c) is differentially expressed in the paired low-metastatic lung cancer cell line 95C compared to the high-metastatic lung cancer cell line 95D. Bioinformatics analysis shows that integrin β1 and matrix metalloproteinase 2 (MMP2) could b...

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Bibliographic Details
Main Authors: Heyong Wang, Yingchao Zhu, Mingchuan Zhao, Chunlian Wu, Peng Zhang, Liang Tang, Huijun Zhang, Xiaofeng Chen, Yaoqin Yang, Gentao Liu
Format: article
Language:EN
Published: Public Library of Science (PLoS) 2013
Subjects:
Medicine
R
Science
Q
Online Access:https://doaj.org/article/75089955be5a43478b9238af2582d7fa
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https://doaj.org/article/75089955be5a43478b9238af2582d7fa

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