Structural characteristics and membrane interactions of tandem α-synuclein oligomers

Abstract Pre-fibrillar oligomers of α-synuclein are thought to be pathogenic molecules leading to neurotoxicity associated with Parkinson’s disease and other neurodegenerative disorders. However, small oligomers are difficult to isolate for study. To gain better insight into the properties of small...

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Autores principales: Chunhua Dong, Marion Hoffmann, Xi Li, Meijing Wang, Craig R. Garen, Nils O. Petersen, Michael T. Woodside
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2018
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Acceso en línea:https://doaj.org/article/753ab479bd164e23b8bc169e752047c5
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