Ploidy and recombination proficiency shape the evolutionary adaptation to constitutive DNA replication stress.
In haploid budding yeast, evolutionary adaptation to constitutive DNA replication stress alters three genome maintenance modules: DNA replication, the DNA damage checkpoint, and sister chromatid cohesion. We asked how these trajectories depend on genomic features by comparing the adaptation in three...
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Autores principales: | , |
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Formato: | article |
Lenguaje: | EN |
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Public Library of Science (PLoS)
2021
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Acceso en línea: | https://doaj.org/article/758b26a78ec04da9b0298c1bdc690338 |
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