Eμ and 3′RR IgH enhancers show hierarchic unilateral dependence in mature B-cells

Abstract Enhancer and super-enhancers are master regulators of cell fate. While they act at long-distances on adjacent genes, it is unclear whether they also act on one another. The immunoglobulin heavy chain (IgH) locus is unique in carrying two super-enhancers at both ends of the constant gene clu...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autores principales: A. Saintamand, C. Vincent-Fabert, M. Marquet, N. Ghazzaui, V. Magnone, E. Pinaud, M. Cogné, Y. Denizot
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
Materias:
R
Q
Acceso en línea:https://doaj.org/article/759dce4b4ff54191badca142fafe61e7
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!

Ejemplares similares