CTCF orchestrates the germinal centre transcriptional program and prevents premature plasma cell differentiation

Activated B cells differentiate into antibody-producing plasma cells in the germinal centre in secondary lymphoid organs. Here the authors show that this differentiation process and related transcription programs are modulated by the transcription factor CTCF, partly by suppressing the premature exp...

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Auteurs principaux: Arantxa Pérez-García, Ester Marina-Zárate, Ángel F. Álvarez-Prado, Jose M. Ligos, Niels Galjart, Almudena R. Ramiro
Format: article
Langue:EN
Publié: Nature Portfolio 2017
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Accès en ligne:https://doaj.org/article/75b203f03cb5452fbe3bed7da17951d3
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