CTCF orchestrates the germinal centre transcriptional program and prevents premature plasma cell differentiation
Activated B cells differentiate into antibody-producing plasma cells in the germinal centre in secondary lymphoid organs. Here the authors show that this differentiation process and related transcription programs are modulated by the transcription factor CTCF, partly by suppressing the premature exp...
Enregistré dans:
| Auteurs principaux: | Arantxa Pérez-García, Ester Marina-Zárate, Ángel F. Álvarez-Prado, Jose M. Ligos, Niels Galjart, Almudena R. Ramiro |
|---|---|
| Format: | article |
| Langue: | EN |
| Publié: |
Nature Portfolio
2017
|
| Sujets: | |
| Accès en ligne: | https://doaj.org/article/75b203f03cb5452fbe3bed7da17951d3 |
| Tags: |
Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!
|
Documents similaires
-
CTCF and transcription influence chromatin structure re-configuration after mitosis
par: Haoyue Zhang, et autres
Publié: (2021) -
CTCF driven TERRA transcription facilitates completion of telomere DNA replication
par: Kate Beishline, et autres
Publié: (2017) -
The transcription factor CBFB suppresses breast cancer through orchestrating translation and transcription
par: Navdeep Malik, et autres
Publié: (2019) -
EAF2 mediates germinal centre B-cell apoptosis to suppress excessive immune responses and prevent autoimmunity
par: Yingqian Li, et autres
Publié: (2016) -
Author Correction: CTCF interacts with the lytic HSV-1 genome to promote viral transcription
par: Fengchao Lang, et autres
Publié: (2021)