LARP7-like protein Pof8 regulates telomerase assembly and poly(A)+TERRA expression in fission yeast

A functional telomerase complex requires that the catalytic TERT subunit be assembled with the template RNA TER1. Here the authors show that Pof8, a possible LARP7 family protein, is required for assembly of the telomerase complex, and repression of lncRNA transcripts at telomeres in S. pombe.

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Autores principales: Amanda K. Mennie, Bettina A. Moser, Toru M. Nakamura
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2018
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Q
Acceso en línea:https://doaj.org/article/75e94b3c5a5045c4a231fd702af774f5
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