LARP7-like protein Pof8 regulates telomerase assembly and poly(A)+TERRA expression in fission yeast

A functional telomerase complex requires that the catalytic TERT subunit be assembled with the template RNA TER1. Here the authors show that Pof8, a possible LARP7 family protein, is required for assembly of the telomerase complex, and repression of lncRNA transcripts at telomeres in S. pombe.

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Autores principales:	Amanda K. Mennie, Bettina A. Moser, Toru M. Nakamura
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2018
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/75e94b3c5a5045c4a231fd702af774f5
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spelling	oai:doaj.org-article:75e94b3c5a5045c4a231fd702af774f52021-12-02T16:49:17ZLARP7-like protein Pof8 regulates telomerase assembly and poly(A)+TERRA expression in fission yeast10.1038/s41467-018-02874-02041-1723https://doaj.org/article/75e94b3c5a5045c4a231fd702af774f52018-02-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-02874-0https://doaj.org/toc/2041-1723A functional telomerase complex requires that the catalytic TERT subunit be assembled with the template RNA TER1. Here the authors show that Pof8, a possible LARP7 family protein, is required for assembly of the telomerase complex, and repression of lncRNA transcripts at telomeres in S. pombe.Amanda K. MennieBettina A. MoserToru M. NakamuraNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-12 (2018)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Amanda K. Mennie Bettina A. Moser Toru M. Nakamura LARP7-like protein Pof8 regulates telomerase assembly and poly(A)+TERRA expression in fission yeast
description	A functional telomerase complex requires that the catalytic TERT subunit be assembled with the template RNA TER1. Here the authors show that Pof8, a possible LARP7 family protein, is required for assembly of the telomerase complex, and repression of lncRNA transcripts at telomeres in S. pombe.
format	article
author	Amanda K. Mennie Bettina A. Moser Toru M. Nakamura
author_facet	Amanda K. Mennie Bettina A. Moser Toru M. Nakamura
author_sort	Amanda K. Mennie
title	LARP7-like protein Pof8 regulates telomerase assembly and poly(A)+TERRA expression in fission yeast
title_short	LARP7-like protein Pof8 regulates telomerase assembly and poly(A)+TERRA expression in fission yeast
title_full	LARP7-like protein Pof8 regulates telomerase assembly and poly(A)+TERRA expression in fission yeast
title_fullStr	LARP7-like protein Pof8 regulates telomerase assembly and poly(A)+TERRA expression in fission yeast
title_full_unstemmed	LARP7-like protein Pof8 regulates telomerase assembly and poly(A)+TERRA expression in fission yeast
title_sort	larp7-like protein pof8 regulates telomerase assembly and poly(a)+terra expression in fission yeast
publisher	Nature Portfolio
publishDate	2018
url	https://doaj.org/article/75e94b3c5a5045c4a231fd702af774f5
work_keys_str_mv	AT amandakmennie larp7likeproteinpof8regulatestelomeraseassemblyandpolyaterraexpressioninfissionyeast AT bettinaamoser larp7likeproteinpof8regulatestelomeraseassemblyandpolyaterraexpressioninfissionyeast AT torumnakamura larp7likeproteinpof8regulatestelomeraseassemblyandpolyaterraexpressioninfissionyeast
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LARP7-like protein Pof8 regulates telomerase assembly and poly(A)+TERRA expression in fission yeast

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