LARP7-like protein Pof8 regulates telomerase assembly and poly(A)+TERRA expression in fission yeast

A functional telomerase complex requires that the catalytic TERT subunit be assembled with the template RNA TER1. Here the authors show that Pof8, a possible LARP7 family protein, is required for assembly of the telomerase complex, and repression of lncRNA transcripts at telomeres in S. pombe.

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Autores principales: Amanda K. Mennie, Bettina A. Moser, Toru M. Nakamura
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Lenguaje:EN
Publicado: Nature Portfolio 2018
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Acceso en línea:https://doaj.org/article/75e94b3c5a5045c4a231fd702af774f5
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spelling oai:doaj.org-article:75e94b3c5a5045c4a231fd702af774f52021-12-02T16:49:17ZLARP7-like protein Pof8 regulates telomerase assembly and poly(A)+TERRA expression in fission yeast10.1038/s41467-018-02874-02041-1723https://doaj.org/article/75e94b3c5a5045c4a231fd702af774f52018-02-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-02874-0https://doaj.org/toc/2041-1723A functional telomerase complex requires that the catalytic TERT subunit be assembled with the template RNA TER1. Here the authors show that Pof8, a possible LARP7 family protein, is required for assembly of the telomerase complex, and repression of lncRNA transcripts at telomeres in S. pombe.Amanda K. MennieBettina A. MoserToru M. NakamuraNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-12 (2018)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Amanda K. Mennie
Bettina A. Moser
Toru M. Nakamura
LARP7-like protein Pof8 regulates telomerase assembly and poly(A)+TERRA expression in fission yeast
description A functional telomerase complex requires that the catalytic TERT subunit be assembled with the template RNA TER1. Here the authors show that Pof8, a possible LARP7 family protein, is required for assembly of the telomerase complex, and repression of lncRNA transcripts at telomeres in S. pombe.
format article
author Amanda K. Mennie
Bettina A. Moser
Toru M. Nakamura
author_facet Amanda K. Mennie
Bettina A. Moser
Toru M. Nakamura
author_sort Amanda K. Mennie
title LARP7-like protein Pof8 regulates telomerase assembly and poly(A)+TERRA expression in fission yeast
title_short LARP7-like protein Pof8 regulates telomerase assembly and poly(A)+TERRA expression in fission yeast
title_full LARP7-like protein Pof8 regulates telomerase assembly and poly(A)+TERRA expression in fission yeast
title_fullStr LARP7-like protein Pof8 regulates telomerase assembly and poly(A)+TERRA expression in fission yeast
title_full_unstemmed LARP7-like protein Pof8 regulates telomerase assembly and poly(A)+TERRA expression in fission yeast
title_sort larp7-like protein pof8 regulates telomerase assembly and poly(a)+terra expression in fission yeast
publisher Nature Portfolio
publishDate 2018
url https://doaj.org/article/75e94b3c5a5045c4a231fd702af774f5
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AT bettinaamoser larp7likeproteinpof8regulatestelomeraseassemblyandpolyaterraexpressioninfissionyeast
AT torumnakamura larp7likeproteinpof8regulatestelomeraseassemblyandpolyaterraexpressioninfissionyeast
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