LARP7-like protein Pof8 regulates telomerase assembly and poly(A)+TERRA expression in fission yeast
A functional telomerase complex requires that the catalytic TERT subunit be assembled with the template RNA TER1. Here the authors show that Pof8, a possible LARP7 family protein, is required for assembly of the telomerase complex, and repression of lncRNA transcripts at telomeres in S. pombe.
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Nature Portfolio
2018
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oai:doaj.org-article:75e94b3c5a5045c4a231fd702af774f52021-12-02T16:49:17ZLARP7-like protein Pof8 regulates telomerase assembly and poly(A)+TERRA expression in fission yeast10.1038/s41467-018-02874-02041-1723https://doaj.org/article/75e94b3c5a5045c4a231fd702af774f52018-02-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-02874-0https://doaj.org/toc/2041-1723A functional telomerase complex requires that the catalytic TERT subunit be assembled with the template RNA TER1. Here the authors show that Pof8, a possible LARP7 family protein, is required for assembly of the telomerase complex, and repression of lncRNA transcripts at telomeres in S. pombe.Amanda K. MennieBettina A. MoserToru M. NakamuraNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-12 (2018) |
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Science Q Amanda K. Mennie Bettina A. Moser Toru M. Nakamura LARP7-like protein Pof8 regulates telomerase assembly and poly(A)+TERRA expression in fission yeast |
description |
A functional telomerase complex requires that the catalytic TERT subunit be assembled with the template RNA TER1. Here the authors show that Pof8, a possible LARP7 family protein, is required for assembly of the telomerase complex, and repression of lncRNA transcripts at telomeres in S. pombe. |
format |
article |
author |
Amanda K. Mennie Bettina A. Moser Toru M. Nakamura |
author_facet |
Amanda K. Mennie Bettina A. Moser Toru M. Nakamura |
author_sort |
Amanda K. Mennie |
title |
LARP7-like protein Pof8 regulates telomerase assembly and poly(A)+TERRA expression in fission yeast |
title_short |
LARP7-like protein Pof8 regulates telomerase assembly and poly(A)+TERRA expression in fission yeast |
title_full |
LARP7-like protein Pof8 regulates telomerase assembly and poly(A)+TERRA expression in fission yeast |
title_fullStr |
LARP7-like protein Pof8 regulates telomerase assembly and poly(A)+TERRA expression in fission yeast |
title_full_unstemmed |
LARP7-like protein Pof8 regulates telomerase assembly and poly(A)+TERRA expression in fission yeast |
title_sort |
larp7-like protein pof8 regulates telomerase assembly and poly(a)+terra expression in fission yeast |
publisher |
Nature Portfolio |
publishDate |
2018 |
url |
https://doaj.org/article/75e94b3c5a5045c4a231fd702af774f5 |
work_keys_str_mv |
AT amandakmennie larp7likeproteinpof8regulatestelomeraseassemblyandpolyaterraexpressioninfissionyeast AT bettinaamoser larp7likeproteinpof8regulatestelomeraseassemblyandpolyaterraexpressioninfissionyeast AT torumnakamura larp7likeproteinpof8regulatestelomeraseassemblyandpolyaterraexpressioninfissionyeast |
_version_ |
1718383404095897600 |