Transmembrane Protein TMEM230, a Target of Glioblastoma Therapy

Transmembrane Protein TMEM230, a Target of Glioblastoma Therapy

Glioblastomas (GBM) are the most aggressive tumors originating in the brain. Histopathologic features include circuitous, disorganized, and highly permeable blood vessels with intermittent blood flow. These features contribute to the inability to direct therapeutic agents to tumor cells. Known targe...

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Main Authors: Cinzia Cocola, Valerio Magnaghi, Edoardo Abeni, Paride Pelucchi, Valentina Martino, Laura Vilardo, Eleonora Piscitelli, Arianna Consiglio, Giorgio Grillo, Ettore Mosca, Roberta Gualtierotti, Daniela Mazzaccaro, Gina La Sala, Chiara Di Pietro, Mira Palizban, Sabino Liuni, Giuseppina DePedro, Stefano Morara, Giovanni Nano, James Kehler, Burkhard Greve, Alessio Noghero, Daniela Marazziti, Federico Bussolino, Gianfranco Bellipanni, Igea D’Agnano, Martin Götte, Ileana Zucchi, Rolland Reinbold
Format: article
Language:EN
Published: Frontiers Media S.A. 2021
Subjects:
cargo vesicle transport
angiogenesis and normalization of vascular network
tumor cell migration and adhesion
anticancer and antiangiogenic therapy
glioma
kinesin motor proteins
Neurosciences. Biological psychiatry. Neuropsychiatry
RC321-571
Online Access:https://doaj.org/article/75f0ce9fbf4943ef8b3abd80f17950d9
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