Granzyme B: A Double-Edged Sword in the Response to Influenza Infection in Vaccinated Older Adults

Background: Influenza-specific cytolytic T lymphocytes (CTL) have a critical role in clearing the virus from the lungs, but are poorly stimulated by current inactivated influenza vaccines. Our previous work suggests that granzyme B (GrB) activity predicts protection against laboratory-confirmed infl...

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Autores principales: Chris P. Verschoor, Graham Pawelec, Laura Haynes, Mark Loeb, Melissa K. Andrew, George A. Kuchel, Janet E. McElhaney
Formato: article
Lenguaje:EN
Publicado: Frontiers Media S.A. 2021
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Acceso en línea:https://doaj.org/article/75f3f32a0eb14c519be15deda1c48049
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