Single molecule secondary structure determination of proteins through infrared absorption nanospectroscopy

While infrared nanospectroscopy methods based on thermomechanical detection (AFM-IR) enables the acquisition of absorption spectra at the nanoscale, single molecule detection has not been possible so far. Here, the authors present off-resonance, low power and short pulse infrared nanospectroscopy (O...

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Bibliographic Details
Main Authors: Francesco Simone Ruggeri, Benedetta Mannini, Roman Schmid, Michele Vendruscolo, Tuomas P. J. Knowles
Format: article
Language:EN
Published: Nature Portfolio 2020
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Online Access:https://doaj.org/article/75fd9014aacf4a8eacc2ca3e369c4d03
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