GSK-3β manipulates ferroptosis sensitivity by dominating iron homeostasis

Abstract Ferroptosis is a newly characterized form of non-apoptotic-programmed cell death, which is driven by the lethal accumulation of iron-catalyzed lipid peroxides. Uncontrolled ferroptosis is implicated in the pathogenesis of a group of human diseases, while targeted induction of ferroptosis pr...

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Auteurs principaux: Lingjuan Wang, Sijin Ouyang, Bin Li, Hao Wu, Fengli Wang
Format: article
Langue:EN
Publié: Nature Publishing Group 2021
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Accès en ligne:https://doaj.org/article/76208c12c0ba4889bc7bc358dddbcf06
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