Are current atomistic force fields accurate enough to study proteins in crowded environments?
The high concentration of macromolecules in the crowded cellular interior influences different thermodynamic and kinetic properties of proteins, including their structural stabilities, intermolecular binding affinities and enzymatic rates. Moreover, various structural biology methods, such as NMR or...
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| Auteurs principaux: | , |
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| Format: | article |
| Langue: | EN |
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Public Library of Science (PLoS)
2014
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| Accès en ligne: | https://doaj.org/article/7679953f98ed4d5a9d411c383742a757 |
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