Neuroinductive properties of mGDNF depend on the producer, E. Coli or human cells.

The glial cell line-derived neurotrophic factor (GDNF) is involved in the survival of dopaminergic neurons. Besides, GDNF can also induce axonal growth and creation of new functional synapses. GDNF potential is promising for translation to treat diseases associated with neuronal death: neurodegenera...

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Autores principales: Dzhirgala V Shamadykova, Dmitry Y Panteleev, Nadezhda N Kust, Ekaterina A Savchenko, Ekaterina Y Rybalkina, Alexander V Revishchin, Galina V Pavlova
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2021
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Acceso en línea:https://doaj.org/article/767fcb299b8c4227b76c2a11ba335bee
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