Proteome-wide analysis of cysteine oxidation reveals metabolic sensitivity to redox stress

Reactive oxygen species can modify cysteine residues on proteins to control cellular signalling. Here, the authors develop a proteomics approach to assess cysteine oxidation dynamics in cells and primary tissues, monitoring oxidative stress-induced metabolic adaptations and oxidation states of biofl...

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Auteurs principaux: Jiska van der Reest, Sergio Lilla, Liang Zheng, Sara Zanivan, Eyal Gottlieb
Format: article
Langue:EN
Publié: Nature Portfolio 2018
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Accès en ligne:https://doaj.org/article/7694b9f783604c42982ffc3181e4b9d1
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