Proteome-wide analysis of cysteine oxidation reveals metabolic sensitivity to redox stress

Reactive oxygen species can modify cysteine residues on proteins to control cellular signalling. Here, the authors develop a proteomics approach to assess cysteine oxidation dynamics in cells and primary tissues, monitoring oxidative stress-induced metabolic adaptations and oxidation states of biofl...

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Autores principales:	Jiska van der Reest, Sergio Lilla, Liang Zheng, Sara Zanivan, Eyal Gottlieb
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2018
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/7694b9f783604c42982ffc3181e4b9d1
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spelling	oai:doaj.org-article:7694b9f783604c42982ffc3181e4b9d12021-12-02T15:33:36ZProteome-wide analysis of cysteine oxidation reveals metabolic sensitivity to redox stress10.1038/s41467-018-04003-32041-1723https://doaj.org/article/7694b9f783604c42982ffc3181e4b9d12018-04-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-04003-3https://doaj.org/toc/2041-1723Reactive oxygen species can modify cysteine residues on proteins to control cellular signalling. Here, the authors develop a proteomics approach to assess cysteine oxidation dynamics in cells and primary tissues, monitoring oxidative stress-induced metabolic adaptations and oxidation states of biofluid proteins.Jiska van der ReestSergio LillaLiang ZhengSara ZanivanEyal GottliebNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-16 (2018)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Jiska van der Reest Sergio Lilla Liang Zheng Sara Zanivan Eyal Gottlieb Proteome-wide analysis of cysteine oxidation reveals metabolic sensitivity to redox stress
description	Reactive oxygen species can modify cysteine residues on proteins to control cellular signalling. Here, the authors develop a proteomics approach to assess cysteine oxidation dynamics in cells and primary tissues, monitoring oxidative stress-induced metabolic adaptations and oxidation states of biofluid proteins.
format	article
author	Jiska van der Reest Sergio Lilla Liang Zheng Sara Zanivan Eyal Gottlieb
author_facet	Jiska van der Reest Sergio Lilla Liang Zheng Sara Zanivan Eyal Gottlieb
author_sort	Jiska van der Reest
title	Proteome-wide analysis of cysteine oxidation reveals metabolic sensitivity to redox stress
title_short	Proteome-wide analysis of cysteine oxidation reveals metabolic sensitivity to redox stress
title_full	Proteome-wide analysis of cysteine oxidation reveals metabolic sensitivity to redox stress
title_fullStr	Proteome-wide analysis of cysteine oxidation reveals metabolic sensitivity to redox stress
title_full_unstemmed	Proteome-wide analysis of cysteine oxidation reveals metabolic sensitivity to redox stress
title_sort	proteome-wide analysis of cysteine oxidation reveals metabolic sensitivity to redox stress
publisher	Nature Portfolio
publishDate	2018
url	https://doaj.org/article/7694b9f783604c42982ffc3181e4b9d1
work_keys_str_mv	AT jiskavanderreest proteomewideanalysisofcysteineoxidationrevealsmetabolicsensitivitytoredoxstress AT sergiolilla proteomewideanalysisofcysteineoxidationrevealsmetabolicsensitivitytoredoxstress AT liangzheng proteomewideanalysisofcysteineoxidationrevealsmetabolicsensitivitytoredoxstress AT sarazanivan proteomewideanalysisofcysteineoxidationrevealsmetabolicsensitivitytoredoxstress AT eyalgottlieb proteomewideanalysisofcysteineoxidationrevealsmetabolicsensitivitytoredoxstress
_version_	1718387088777281536

Proteome-wide analysis of cysteine oxidation reveals metabolic sensitivity to redox stress

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