Assessment of hepatic detoxification activity: proposal of an improved variant of the (13)c-methacetin breath test.

Breath tests based on the administration of a (13)C-labeled drug and subsequent monitoring of (13)CO2 in the breath (quantified as DOB - delta over baseline) liberated from the drug during hepatic CPY-dependent detoxification are important tools in liver function diagnostics. The capability of such...

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Autores principales: Hermann-Georg Holzhütter, Johan Friso Lock, Pouria Taheri, Sascha Bulik, Andrean Goede, Martin Stockmann
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2013
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Acceso en línea:https://doaj.org/article/76a0cfe3c10845c2b90c268cd6a5ffd1
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