PRMT5-mediated regulation of developmental myelination

PRMT5-mediated regulation of developmental myelination

Myelin-forming cells derive from oligodendrocyte progenitors. Here the authors identify histone arginine methyl-transferase PRMT5 as critical for developmental myelination by modulating the cross-talk between histone arginine methylation and lysine acetylation, to favor differentiation.

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Detalles Bibliográficos
Autores principales: Antonella Scaglione, Julia Patzig, Jialiang Liang, Rebecca Frawley, Jabez Bok, Angeliki Mela, Camila Yattah, Jingxian Zhang, Shun Xie Teo, Ting Zhou, Shuibing Chen, Emily Bernstein, Peter Canoll, Ernesto Guccione, Patrizia Casaccia
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2018
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Science
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Acceso en línea:https://doaj.org/article/76b30499e5d34bdbba4aa57b8416de06
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https://doaj.org/article/76b30499e5d34bdbba4aa57b8416de06

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