PRMT5-mediated regulation of developmental myelination

Myelin-forming cells derive from oligodendrocyte progenitors. Here the authors identify histone arginine methyl-transferase PRMT5 as critical for developmental myelination by modulating the cross-talk between histone arginine methylation and lysine acetylation, to favor differentiation.

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Detalles Bibliográficos
Autores principales:	Antonella Scaglione, Julia Patzig, Jialiang Liang, Rebecca Frawley, Jabez Bok, Angeliki Mela, Camila Yattah, Jingxian Zhang, Shun Xie Teo, Ting Zhou, Shuibing Chen, Emily Bernstein, Peter Canoll, Ernesto Guccione, Patrizia Casaccia
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2018
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/76b30499e5d34bdbba4aa57b8416de06
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spelling	oai:doaj.org-article:76b30499e5d34bdbba4aa57b8416de062021-12-02T17:31:11ZPRMT5-mediated regulation of developmental myelination10.1038/s41467-018-04863-92041-1723https://doaj.org/article/76b30499e5d34bdbba4aa57b8416de062018-07-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-04863-9https://doaj.org/toc/2041-1723Myelin-forming cells derive from oligodendrocyte progenitors. Here the authors identify histone arginine methyl-transferase PRMT5 as critical for developmental myelination by modulating the cross-talk between histone arginine methylation and lysine acetylation, to favor differentiation.Antonella ScaglioneJulia PatzigJialiang LiangRebecca FrawleyJabez BokAngeliki MelaCamila YattahJingxian ZhangShun Xie TeoTing ZhouShuibing ChenEmily BernsteinPeter CanollErnesto GuccionePatrizia CasacciaNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-14 (2018)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Antonella Scaglione Julia Patzig Jialiang Liang Rebecca Frawley Jabez Bok Angeliki Mela Camila Yattah Jingxian Zhang Shun Xie Teo Ting Zhou Shuibing Chen Emily Bernstein Peter Canoll Ernesto Guccione Patrizia Casaccia PRMT5-mediated regulation of developmental myelination
description	Myelin-forming cells derive from oligodendrocyte progenitors. Here the authors identify histone arginine methyl-transferase PRMT5 as critical for developmental myelination by modulating the cross-talk between histone arginine methylation and lysine acetylation, to favor differentiation.
format	article
author	Antonella Scaglione Julia Patzig Jialiang Liang Rebecca Frawley Jabez Bok Angeliki Mela Camila Yattah Jingxian Zhang Shun Xie Teo Ting Zhou Shuibing Chen Emily Bernstein Peter Canoll Ernesto Guccione Patrizia Casaccia
author_facet	Antonella Scaglione Julia Patzig Jialiang Liang Rebecca Frawley Jabez Bok Angeliki Mela Camila Yattah Jingxian Zhang Shun Xie Teo Ting Zhou Shuibing Chen Emily Bernstein Peter Canoll Ernesto Guccione Patrizia Casaccia
author_sort	Antonella Scaglione
title	PRMT5-mediated regulation of developmental myelination
title_short	PRMT5-mediated regulation of developmental myelination
title_full	PRMT5-mediated regulation of developmental myelination
title_fullStr	PRMT5-mediated regulation of developmental myelination
title_full_unstemmed	PRMT5-mediated regulation of developmental myelination
title_sort	prmt5-mediated regulation of developmental myelination
publisher	Nature Portfolio
publishDate	2018
url	https://doaj.org/article/76b30499e5d34bdbba4aa57b8416de06
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PRMT5-mediated regulation of developmental myelination

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