Japanese encephalitis virus live attenuated vaccine strains display altered immunogenicity, virulence and genetic diversity

Abstract Japanese encephalitis virus (JEV) is the etiological agent of Japanese encephalitis (JE). The most commonly used vaccine used to prevent JE is the live-attenuated strain SA14-14-2, which was generated by serial passage of the wild-type (WT) JEV strain SA14. Two other vaccine candidates, SA1...

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Bibliographic Details
Main Authors: Emily H. Davis, Andrew S. Beck, Li Li, Mellodee M. White, Marianne Banks Greenberg, Jill K. Thompson, Steven G. Widen, Alan D. T. Barrett, Nigel Bourne
Format: article
Language:EN
Published: Nature Portfolio 2021
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Online Access:https://doaj.org/article/76c97446ba9048d6a3eb3659558a8afe
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