<italic toggle="yes">SLC6A14</italic> Is a Genetic Modifier of Cystic Fibrosis That Regulates <italic toggle="yes">Pseudomonas aeruginosa</italic> Attachment to Human Bronchial Epithelial Cells

<italic toggle="yes">SLC6A14</italic> Is a Genetic Modifier of Cystic Fibrosis That Regulates <italic toggle="yes">Pseudomonas aeruginosa</italic> Attachment to Human Bronchial Epithelial Cells

ABSTRACT Cystic fibrosis (CF) is caused by mutations in the CFTR gene and is associated with progressive and ultimately fatal infectious lung disease. There can be considerable variability in disease severity among individuals with the same CFTR mutations, and recent genome-wide association studies...

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Autores principales: Michelle Di Paola, Amber J. Park, Saumel Ahmadi, Elyse J. Roach, Yu-Sheng Wu, Michaela Struder-Kypke, Joseph S. Lam, Christine E. Bear, Cezar M. Khursigara
Formato: article
Lenguaje:EN
Publicado: American Society for Microbiology 2017
Materias:
CFTR mutation
l-arginine uptake
Pseudomonas aeruginosa
SLC6A14
airway epithelia
bacterial colonization
Microbiology
QR1-502
Acceso en línea:https://doaj.org/article/76ee622aef314119b45318ab4b87d2aa
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https://doaj.org/article/76ee622aef314119b45318ab4b87d2aa

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