Autophagy Flux Correlates with Upregulation of AKT-1 in RAS Mutated Colon Cancer Cells
Background: The AKT/PKB (protein kinase B) kinase is the main regulator of autophagy in mammalian cells, which consists of three isoforms, including AKT-1, AKT-2, and AKT-3. Rat sarcoma viral oncogene homolog (RAS), known as the most frequently mutated oncogene in colorectal cancers, is one of the m...
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| Autores principales: | , , , |
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| Formato: | article |
| Lenguaje: | EN |
| Publicado: |
Shiraz University of Medical Sciences
2021
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| Materias: | |
| Acceso en línea: | https://doaj.org/article/76fdd070a5904d649ed9b484e1c92863 |
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