In Vitro Ciliotoxicity and Cytotoxicity Testing of Repeated Chronic Exposure to Topical Nasal Formulations for Safety Studies
Certain active drugs and excipients of nasal formulations may impair ciliary function and mucociliary clearance. The ciliary beat frequency (CBF) is a key parameter for determining mucociliary clearance rate, and in vitro assessments of CBF have proven to be accurate and reproducible. Since topical...
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Formato: | article |
Lenguaje: | EN |
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MDPI AG
2021
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Acceso en línea: | https://doaj.org/article/775667f3be4745bda76638b29ea4b91d |
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